Significant speed improvements over previous iterations.
Navigate to the folder where you downloaded the Vina file (usually named something like autodock_vina_1_1_2_linux_x86.tgz or autodock_vina_1_1_2_win32.zip ).
Repeat a similar preparation process for your small molecule, defining its rotatable bonds, and save it as ligand.pdbqt . Step 2: Define the Search Space (Grid Box) autodock vina 112 download verified
Autodock Vina 1.1.2 is a widely-used and reliable molecular docking software that offers a fast and accurate way to predict the binding affinity and orientation of small molecules to a specific protein target. By following the verified download and installation steps outlined in this article, researchers can easily obtain and use Autodock Vina 1.1.2 for their molecular docking studies.
To acquire a verified version of the software, you should source your files directly through the following trusted channels: Significant speed improvements over previous iterations
It is crucial to note that v1.1.2 (last revision: May 2011) is the final version of the AutoDock Vina. While active development has since moved to newer engines like v1.2.x (2021–present) and AutoDock-GPU, version 1.1.2 remains a widely cited scientific benchmark and is still supported on many legacy systems and high-performance computing (HPC) clusters. The official legacy site, vina.scripps.edu , acknowledges that this version has been superseded but is kept open for informational purposes.
Once you have a verified copy of the software, you can proceed with installation. The approach depends on your operating system and needs. Below is an overview of the primary methods. Step 2: Define the Search Space (Grid Box) Autodock Vina 1
Type vina --help in the terminal to verify successful installation. For macOS Users
In the rapidly evolving world of computational chemistry and drug discovery, stands out as a foundational tool. As of May 2026, researchers and students continue to rely on the robust, high-performance capabilities of AutoDock Vina 1.1.2 for molecular docking simulations.
It performs molecular docking to calculate the binding affinity of a ligand-receptor complex.
This dictates the time spent searching for the global minimum. The default value is 8 . Increasing it improves accuracy but requires more processing power. Step 4: Run the Docking Execution
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